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A: Purity is critical

Intranasal powder formulations have been shown to be advantageous compared with liquid formulations because they provide improved stability, prolonged drug residence time on the nasal mucosa, and enhanced bioavailability (Tiozzo Fasiolo et al., 2018)

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That is a real risk arguably a greater one than the theoretical risks the FDA cited when it enacted the 2023 restrictions

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Duffy JP, Eibl G, Reber HA, Hines OJ