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When rosuvastatin and other statins lower LDL-C by reducing hepatic cholesterol synthesis, they may modestly reduce the substrate available for cutaneous vitamin D synthesis triggered by UVB exposure

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The development of melanocytes in utero is regulated by c-Met (MET proto-oncogene, receptor tyrosine kinase) and c-Kit (V-Kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologue) [92, 93]

Addressing these gaps will be essential to clarify the functional relevance of ferroptosis in kidney stone disease and unlock its potential as a therapeutic target