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Additional benefits included improvements in waist circumference, lipid profiles, and blood pressure

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While the major uses for GLP-1s include those with type 2 diabetes and obesity, in March of 2024, the FDA also approved them for heart diseases

Semaglutide is degraded by proteolytic enzymes and does not rely on hepatic cytochrome P450 metabolism, whilst topiramate undergoes limited hepatic metabolism and is primarily excreted unchanged in urine

Comparative Effectiveness of Long-Acting GLP-1 Receptor Agonists in Type 2 Diabetes: A Short Review on the Emerging Data

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