While our study included only women treated within the year before documented fertility-related events, we could not confirm adherence to this washout period, and it remains possible that physiological or residual pharmacologic effects persisted, influencing outcomes
We provide access to compounded semaglutide, which is prepared in FDA-registered and inspected compounding pharmacies
The trial compared injectable semaglutide (1mg) once weekly with a placebo as an adjunct to the standard of care for the prevention of major kidney outcomes, specifically kidney failure, substantial loss of kidney function, and death from kidney or cardiovascular causes
Elevated IGF-1 beyond the upper physiological range raises concerns about downstream effects, including fluid retention, carpal tunnel syndrome, and theoretical long-term risks requiring further evaluation
Five times the dose from the same syringe marking
The principle is universal across all injectable peptides