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2025;15:1649801.[DOI] Copyright The Author(s) 2026

A significant change in pH affects the structure of all macromolecules, for instance, presence of a higher proportion of H + or low pH solution cleaves DNA double helix strands by protonating the DNA phosphodiester groups and consequently destabilizing the hydrogen bonds linking DNA nitrogenous bases guanine and cytosine (G-C) ( E

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Severe asthma with fungal sensitization (SAFS) is a recognized clinical entity in which patients have markedly poorer outcomes than non-sensitized asthmatics

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The confluence of sex hormones and aging on immunity