Abbreviations CVE: Cardiovascular event EHR: Electronic health record GLP-1RA: Glucagon-like peptide-1 receptor agonist MACE: Major adverse cardiovascular events NAFLD: Non-alcoholic fatty liver disease NASH: Non-alcoholic steatohepatitis PCI: Percutaneous coronary intervention PSM: Propensity score matching SGLT2: Sodiumglucose cotransporter 2 SMD: Standardised mean difference TG: Triacylglycerol References Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M (2016) Global epidemiology of nonalcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence, and outcomes
Among current and previous GLP-1 users, 60.84% said they were concerned about injecting themselves before starting treatment, including 20.89% who said they were very concerned
All patients initiated injectable semaglutide or tirzepatide for obesity or type 2 diabetes and stopped the medication within three to 12 months
Situations like this are becoming increasingly common as GLP-1 medications move across multiple corners Read More Are GLP-1 Drugs Being Prescribed Too Early
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Early demand for oral GLP-1s is likely to come from people already familiar with weight loss treatments, before awareness spreads more widely into the general public