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The absence of metabolite rescue experiments makes it impossible to rule out the possibility that SSP upregulation represents an adaptive response following resistance acquisition (126)

Venter H, Genade S, Mouton R, Huisamen B, Harper IS, Lochner A

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Elevated lipid peroxidation products and increased lipoxygenase (LOX) activity have also been documented in PD brains, further implicating the ferroptosis axis in DA neuron loss (Maher et al., 2020)