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Research 6 , 0281 (2023)
Paxlovid (nirmatrelvir/ritonavir) Disease area(s): Infectious diseases (antivirals) Manufacturer(s): Pfizer 2024 Sales (USD): $5.72 billion Why it sold so well: In 2024, Pfizers COVID-19 antiviral treatment, Paxlovid, generated $5.72 billion in global revenue, making it the companys third-highest-selling product for the year
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In his foundational report with Thaler, a tripeptide purified from human serum was shown to prolong the survival of cultured normal liver cells while also stimulating growth in neoplastic (hepatoma) liver cells an early hint both of the molecules regenerative signaling and of the fact that its growth-modulating activity is context-dependent rather than uniformly benign
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