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These receptors sit on a variety of cell types, including melanocytes in the skin, where they help regulate melanin production

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It often attains millimolar levels inside cells, which makes it one of the most highly concentrated intracell

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In humans, this enzyme family serves as one of the critical antioxidant mechanisms, readily scavenging reactive oxides and peroxides that are naturally or exogenously produced, protecting cells and structures from oxidative damage 31