The formulation contained excipients including histidine hydrochloride, arginine hydrochloride, histidine, sucrose, polysorbate 80, hydroxypropyl cellulose, glycerol, and benzalkonium chloride (0.005%) (ClinicalTrials.gov, 2023)
Atkins MB, Mier JW, Parkinson DR, Gould JA, Berkman EM, Kaplan MM
Ben Coakley , Owner the Waypoint Company and RX Insurance Group
This observation aligns with previous work showing that pharmacological inhibition or genetic ablation of NMDA receptors in agouti-related-protein (AgRP)-expressing neurons alters synaptic adaptation to fasting 39,40
This means evaluating and optimizing estrogen, progesterone, testosterone, thyroid hormones, and cortisol not just focusing on one piece of the puzzle
If a patient is simultaneously starting or adjusting escitalopram, clinicians might consider staggering these changes to better identify which medication may be responsible for any emerging side effects