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Ozempic/Wegovy (semaglutide) , Novo Nordisks GLP-1 receptor agonist, has patent protection running through the early 2030s in most markets, though the precise timeline is subject to ongoing litigation from generic and biosimilar challengers who are already preparing entry strategies [39]

It is used in a medically supervised plan with regular follow-ups and adjustments

Hyperglycemia or Hypoglycemia with Changes in Insulin Regimen: Changes in an insulin regimen (e.g., insulin strength, manufacturer, type, injection site or method of administration) may affect glycemic control and predispose to hypoglycemia or hyperglycemia

doi: 10.21608/ejchem.2021.80924.4033

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120 In an uncontrolled trial in 32 women with PCOS and obesity, 12 weeks of daily treatment with 400 mg ALA resulted in reduced insulin and glucose levels, BMI, and a measure of insulin resistance