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10.1016/j.bbagen.2012.10.005 45 MakovecT

Cardiovascular effects: Semaglutide has demonstrated favorable cardiovascular outcomes and lowered risk of major cardiovascular events in high-risk individuals with Type 2 Diabetes

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Not only that but you end up with increased amounts of oxidants which have been linked to accelerate the ageing process

doi: 10.1136/GUTJNL-2012-302578 56 DuncanS

Instead, the program may cover semaglutide (the generic equivalent) only if a patient has type 2 diabetes diagnosed first, or if they can demonstrate a documented medical comorbiditysuch as cardiovascular disease or severe sleep apneathat makes obesity a secondary treatment target rather than a primary one