Environmental Conditions : Exposure to high temperatures, moisture, and light can accelerate degradation

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LF: analysis and interpretation of data
doi: 10.1016/j.gene.2018.09.019 55
Certain medications may also interfere with absorption and cause deficiency, in particular, medicines prescribed for heartburn, antibiotics, blood pressure medicine, cholesterol-lowering drugs, diabetes medications and antipsychotic drugs
Results vary and depend on diet, exercise, and individual metabolic factors