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Oxidized semaglutide may have reduced receptor binding affinity, meaning it is less effective at activating the GLP-1 receptor

Fornaro M et al

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Understanding FDAs Compounding Regulations and Semaglutide Compounding semaglutide is feasible under certain conditions, such as in the case of shortages under the Federal Food, Drug, and Cosmetic Act

Temperature requirements Compounded semaglutide should be stored in the refrigerator at 36-46 degrees Fahrenheit (2-8 degrees Celsius)