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Possible temporary reactions include mild soreness at the injection site, nausea, headache, or dizziness for a day or two, and occasional minor bruising

Other possible causes of a vitamin B12 deficiency pernicious anemia prolonged use of certain medications, such as metformin following a strict vegan or vegetarian diet certain infections, such as with the tapeworm Diphyllobothrium latum celiac disease older age high intake of alcohol Other nutritional supplements may also benefit someone with Crohns disease

J., Mehta, H., Hevener, A

Cohort 2 (from June 2026) covers BMI 35 to 39.9 with four or more conditions

But it has not been ruled out, and the FDA's briefing documents noted it as an uncharacterized risk requiring further investigation before any approval

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