Moreover, they are critical during childhood for the proper growth and development of bones and tissues (Bassett and Williams 2016), Fig
Nature 464 , 121125 (2010)
For instance, P115 and GRASP65 trigger apoptosis via the ERK/p53/PUMA pathway or Fas-mediated signaling, respectively, whereas Bruce and GAAP decrease apoptosis via caspase-9, Smac and p53 inhibition, and Ca 2+ signaling downregulation [93]
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