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M., Dietrich B., Hiersemenzel R.: harmacoelectroencephalographic and clinical effects of the cholinergic substance acetyl-L-carnitine in patients with organic brain syndrome

This influx of free carnitine overcomes the rate-limiting bottleneck at the CPT1 enzyme, allowing the cell to rapidly convert accumulated long-chain fatty acids into acylcarnitines

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An omega-3 fatty acid found in the human brain and the meat of fatty fish

Experiments with fasted and calorie-restricted rats showed increased mRNA concentrations of acyl-CoA and CPT-1 in the liver, heart and kidneys compared to control animals due to upregulation of PPAR [111]