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While the main substance patent for semaglutide is expected to expire in 2026, other patents, especially those covering specific formulations, uses, and delivery devices, may extend protections into the 2030s, effectively delaying generic entry

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Heart failure events were not increased in EXAMINE [alogliptin, HR = 1.07 (124)], TECOS [sitagliptin

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In December 2022, as demand for all GLP-1 drugs skyrocketed with the news that they could be safe and effective for obesity and weight management, FDA included tirzepatide on its shortage list, which opened the floodgates for compounded copies

Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins