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And I know I've told your listeners before, over 90% of the products in the operating room have never been through an FDA human safety trial

Conventional copper-modulating therapies, including chelators (e.g., TTM and TETA) and the ionophore elesclomol, are fundamentally limited by their lack of specificity, which constrains their clinical utility and leads to significant adverse effects

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[DOI] [PubMed] [Google Scholar] 23.Richard D, Kefi K, Barbe U, Bausero P, Visioli F

However, LCACs promote the formation of a tetrodotoxin (TTX)-sensitive late Na + current (I Na(L ) ) that exhibits a markedly prolonged channel inactivation period and drives an increase in intracellular Na + concentration (Wu and Corr, 1994)

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