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Almost monthly theyre coming out with new indications that these drugs, either semaglutide or tirzepatide, are appropriate forfrom Parkinsons to cardiovascular disease, even addiction. The drug makers themselves hyped them in television commercials and more

in PARADIGM-HF showed use of angiotensin receptor-neprilysin inhibitor compared to enalapril, an ACEi, not only reduced risk for cardiovascular death and hospitalization related to heart failure, but also decreased the symptoms and physical limitations of heart failure

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Cancer Lett 2006;243:170192