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2 Production and metabolism of TMAO TMAO is formed by the transformation of TMA in the liver, and this process can not be separated from the flavin containing monooxygenase 3 (FMO3) ( Clostridium , Proteus , Shigella , and Aeromonas (Xiong et al., 2023)
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doi: 10.1038/s41392-023-01569-3 Summary Keywords arginine metabolism, glutamine metabolism, immunometabolism, metabolic reprogramming, therapeutic targeting, tryptophan catabolism Citation Yin Y, Yan C, Pei X, Rao J, Wu L, Xue Y, Sun H and Sheng Y (2026) Amino acid metabolism modulates macrophage polarization: implications for autoimmune-related diseases
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