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82 6.5'Effects'of'glutathione'depletion'on'reprogramming'and'enhanced'tumor' growth' Given the fact that glutathione depletion has been tested frequently in the context of cancer therapy [158, 159], it was surprising to observe that the knockout of Gclc was not only compatible with survival, but enabled a strongly accelerated tumor onset, indicating a more aggressive phenotype

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Indeed, the balance between saturated (SFA), mono (MUFA), and polyunsaturated FA (PUFA) is essential for cellular homeostasis and biological functions (Dyall et al, 2022)

Khodashahi, M., Saadati, N., Rezaieyazdi, Z., Sahebari, M

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Fraser, P