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Consistent with the effects in rat PSCs, high glucose and TGF1 levels enhanced the proliferation and decreased the apoptosis of PSCs in the LG group, whereas GSH and SB431542 prevented the effects induced by high glucose

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In clinical samples, the potential effects of long-term treatment with antidepressants, antipsychotics, and other mood stabilizers cannot be fully excluded

Pricing reflects PlexusDx published rates as of April 2026

After receiving 28 days of treatment, different dose groups of ZSP601 showed significant improvements in metabolism, hepatic fat content, inflammation and fibrosis biomarker indices (262), supporting the evaluation of its long-term safety and efficacy in a larger sample size of MASH patients

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