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In conditions of venous congestion, the inflammatory response in endothelial cells is also activated, further exacerbating kidney damage [69, 70]

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Indeed, if glycolysis is the main fuel source for seizures, and a switch from glycolysis to OXPHOS is necessary for proliferating new-born neurons to differentiate into mature neurons in the cortex, it is possible that dysregulation in the glycolysis/OXPHOS switch may be contributing to the pool of immature neurons that ultimately result in seizures in MCD

AKD may progress to CKD or occur during the course of CKD

In addition, access is limited to lifestyle medicine approaches for obesity and its comorbidities