People who are pregnant or breastfeeding should avoid both drugs because they may harm the fetus and its unclear how much of the drugs are passed through breast milk
A double blinded placebo controlled study using daily Orfoglipron (45 mg) in obese patients, found an average of 12.4% decrease in body weight over placebo after 36 weeks
The search strategy was: (Obese Fertile Men OR Functional hypogonadism OR "Diabetes Mellitus, Type 2"[Mesh] OR "Erectile Dysfunction"[Mesh]) AND ("Glucagon-Like Peptide-1 Receptor Agonists"[Mesh] OR semaglutide OR liraglutide OR dulaglutide OR exenatide OR lixisenatide OR tirzepatide) AND (Before treatment OR "Testosterone"[Mesh])
C-peptide levels in latent autoimmune diabetes in adults treated with linagliptin versus glimepiride: exploratory results from a 2-year double-blind, randomized, controlled study
Lets delve into the factors driving this positive shift
Both specialists can prescribe weight loss medications, but their expertise differs in significant ways