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(12) The growing number of orthopedic patients with obesity thus underscores an urgent need for interventions that target both weight reduction and metabolic optimization, offering the potential to improve overall surgical safety and long-term musculoskeletal health

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These effects include promoting cell survival/proliferation, 52,53 migration/invasion, 53,54 oncogenic transformation, 55,56 and epithelial-to-mesenchymal transition, 54,57,58 as well as promoting tumor angiogenesis 59 and lymphangiogenesis 60 and enhancing a cancer stem cell-like phenotype

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If lymph nodes become swollen during GLP-1 treatment, the cause is typically unrelated to the medication and requires clinical evaluation to identify the underlying reason, such as infection or other medical conditions

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