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The mean age of participants was 53 years, mean HbA 1c was 66 mmol/mol (8.2%), mean duration of diabetes was 5.6 years, mean FPG was 9.1 mmol/l and mean body weight was 79.5 kg

That approval moved the semaglutide weight management drug market further away from a lifestyle framing and closer to a treatment model tied to serious clinical outcomes, which has direct consequences for payer discussions, physician confidence, and long-term adherence support

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[1] [23] Your doctor should review important safety information with you, including the boxed warning regarding thyroid C-cell tumors and contraindications for patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

But certain presentations consistently produce faster, more dramatic before and after outcomes

Your GP can perform a clinical examination and arrange further investigations if necessary