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The importance of mGSH is mainly based on its detoxification of hydrogen peroxide, mitochondrial lipid membrane peroxidation, or xenobiotics under the catalysis of enzymes such as GPX or GST [58]

Its clinical manifestations include itchy, erythematous papules and patches, and sometimes vesicles arranged in a reticular pattern (234, 235)

Pyroglutamic acidemia: A cause of high anion gap metabolic acidosis

Judge, A

It has been postulated before that either residue Sec498 hTrxR1 or residue Cys497 hTrxR1 attacks the intra-molecular hTrx1-disulphide (Cys32 hTrx1 , Cys35 hTrx1 ), forming an inter-molecular disulphide bond between hTrx1 and hTrxR1 during catalysis 23

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