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It may possess cardiometabolic actions with the potential to improve the cardiovascular risk profile of patients with T2DM

Chronic studies in rats given 200 mg/kg body weight per day for 104 weeks, dogs given 20 mg/kg PO x 84 days, cats given 40-65 mg/kg for 118 days did not produce any signs of toxicity (blood testing, liver histology)

Medications such as Ozempic, Wegovy, Rybelsus, Mounjaro, and Zepbound mimic or enhance this hormone's effects

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It is a wellness product formulated with nutrients and botanicals commonly associated with metabolic support

Remarkably, in our GLP-1RFab7F38 structure, since no peptide ligand is bound to the orthosteric pocket, the peptide-binding groove of the ECD is juxtaposed with the TMD interacting with ECL1 and ECL3