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GLP-1 receptor agonists, such as semaglutide (sold under the brand name Ozempic or Wegovy) and tirzepatide (brand name Mounjaro or Zepbound), are medications originally developed for diabetes and now approved for chronic weight management at specific doses

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A meta-analysis of 35 randomized trials showed that creatine supplementation significantly increased lean body mass by 0.68 kg overall, rising to 1.1 kg when combined with resistance training

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eNeuro (2019)