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The once-weekly injectable was originally used to help manage diabetes but gained FDA approval in 2021 for "chronic weight management." It suppresses appetite by balancing out the body's hunger hormones and delaying digestion, and has been shown to lead to a 15% to 20% loss of body weight over 68 weeks, Insider's Gabby Landsverk previously reported

Some patients worry that magnesium might reduce semaglutide's effectiveness

Monitor for weight loss, metabolic markers, side effects, and adjust dosing upward only as needed

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muciniphila , no indications of GLP-1 induction have been reported, which questions the relevance of P9 as a signaling protein [41,83]