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In our cryoEM data we identified classes corresponding to a dimer and tetramer of LPLbut not the monomer or trimer, which we observed only in solution by mass photometry and crosslinking

Media (with or without tirzepatide) was replaced once after 44 h

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3.3 Ferroptosis and IBD Acute inflammation constitutes a protective response to infection or tissue injury

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Starting with a murine ileum explant model, the authors showed that intraluminal LPS could stimulate GLP-1 secretion and that GLP-1 secretion was rapidly increased after direct LPS stimulation of an EEC cell line (STC-1 cells)