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how soon after initiation of treatment did the patients go on to develop DME between control and those treated with GLP-1 agonists

Additional unknown risks and side effects: Because berberine and semaglutide havent been studied together, we simply dont know the full range of risks and side effects

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Importantly, chronic peripheral antagonism of the GLP-1R for one week produced additional food intake and weight gain in high-fat dietfed obese mice (4)

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