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Hunger may increase noticeably by day 21-28 after your final injection, signaling that drug concentrations have fallen below levels needed for strong appetite suppression

Pre-renal acute kidney injury may result from GI symptoms (vomiting, diarrhea), which contribute to dehydration and hypovolemia

The weight loss data comes from continuous use, and what happens after stopping, including likely appetite return and possible regain, is poorly documented

GLP-1 weight loss medication is designed to mimic a hormone naturally produced by your intestines