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As an experimental triple receptor agonist that targets the GLP-1, GIP, and glucagon pathways, retatrutide has gotten a lot of attention for its possible use in studying glucose metabolism, weight control, and other metabolic processes

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Other medication-related exclusions included use of antiobesity medications, nutritional supplements or over-the-counter products for weight loss within 3 months prior to screening

Weight loss timeline Clinical trials of semaglutide show a predictable weight loss trajectory