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Goedeke, S., Murphy, T., Rush, A., & Zinn, C

These include tobacco smoking (which can reduce melatonin levels), excessive caffeine consumption (especially in the evenings, which can disrupt natural sleep patterns), and alcohol intake (which can reduce melatonins sleep-inducing effects)

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doi: 10.1016/j.molmet.2018.09.009 45 GarveyWTFriasJPJastreboffAMle RouxCWSattarNAizenbergDet al

Insulin receptors are widely distributed in the central nervous system of the rat