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b , c ) Smad3 gene expression levels in iSPN + at 3 M (Control vs Mutant, p = 0.2) and 8 M (Control vs Mutant, p = 0.004 **)

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Somit wurden einige Substanzen frhzeitig als Vitamine deklariert, die den spter festgesetzten Vitaminkriterien, beispielsweise dem Kriterium der Essentialitt, nicht entsprechen konnten