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Trypsin, thermolysin, and elastase were selected as representative proteases that cover a broad range of cleavage specificities relevant to coronavirus spike activation: trypsin cleaves at basic residues and mimics TMPRSS2 activity 10

Such programs will unlikely work for all or even most individuals

This option allows healthcare providers to adjust treatment gradually, which can be especially helpful for women sensitive to side effects like nausea or fatigue

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(STEP 5) Rubino D, et al