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For the purpose of determining the ACO's prior participation in the BASIC track's glide path, CMS considers whether the ACO satisfies either of the following: (A) The ACO is the same legal entity as a current or previous ACO that previously entered into a participation agreement for participation in the BASIC track's glide path

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Tirzepatide (Zepbound) is also FDA-approved for chronic weight management (with criteria) and has strong trial evidence for substantial average weight loss

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Data were analyzed using BIAcore T200 evaluation software, yielding a dissociation constant (K D ) of 7.858 M for the interaction between DRP1 and KU-57788 (Fig