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His team subsequently identified the specific synapses, cells and circuits in the lateral habenula that are altered by chronic stress in these particular mice, and in collaboration with Csaba Fldy and colleagues at the University of Zrich, they found genes that are overexpressed as well

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At 3 months, 59% of the MPT group reported moderate or marked improvement compared to 26% in the GTM group a statistically significant difference

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