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Proinflammatory cytokines in osteoarthritis Proinflammatory cytokines secreted by chondrocytes, fibroblasts, and immune cells are mediators of the metabolic imbalance and they enhance catabolism by stimulating MMP synthesis in OA-affected joints [24]

Although Lurcher mice were able to find the platform often without any external help and to learn, as demonstrated by escape latency shortening [180], their escape latency was always longer than that of WT mice in both the visible and hidden platform tasks in the MWM [165,166,167,168,169,170]

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This group dependent relationship of TIMP-2 and GSH suggests GSH could still be implicated in PTSD

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