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These models often incorporate results from large cardiovascular outcomes trials such as LEADER, SUSTAIN-6, REWIND, and SELECT

PMID 34221501

Arnott C, Neuen BL, Heerspink HJL et al (2020) The effects of combination canagliflozin and glucagon-like peptide-1 receptor agonist therapy on intermediate markers of cardiovascular risk in the CANVAS program