Funding This work was supported by JST CREST Grant Number JPMJCR2024 (20348438 to T.A.), a Grant-in-Aid for Challenging Exploratory Research (22K19397 to T.A.), a Grant-in-Aid for Scientific Research on Innovative Areas (A) Sulfur biology (21H05263 to T.A., 21H05267 to T.S., and 21H05258 to T.A
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This once-weekly medication, approved for type 2 diabetes and chronic weight management, has a five-day half-life that provides some scheduling flexibility
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The active substance, semaglutide, works by mimicking the GLP-1 hormone, which regulates appetite by increasing feelings of fullness and reducing hunger and cravings
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