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Diabetes Obes Metab 15 , 153163, (2013)

Data from Phase III TRONTIER studies, planned for 2025 initiation, are highly anticipated, with early biomarker data expected in 2026

Stimulation of these receptors could theoretically increase sympathetic outflow, leading to a mild chronotropic (heart rate-increasing) effect

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35 SLC2A1/GLUT1 is a critical transporter for glucose uptake in the brain, induced by hypoxia, and associated with increased glycolysis during carcinogenesis

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