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Some ingredients like lemon can cause photosensitivity

While not common in the US, zinc deficiency can cause higher incidences of infection and increased inflammatory cytokines

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In ischemia/reperfusion (I/R) injury, exRNA directly induces cardiomyocyte apoptosis via the TLR3/TRIF pathway while upregulating TNF- expression

Some IGF-1 derivatives, such as the GPE derivative, made up of just the last three N-terminal amino acids of the IGF-1 protein, have been shown to have therapeutic effects in neurological injuries like stroke