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Hypoxia a key regulatory factor in tumour growth

Protective role of sirtuin3 (SIRT3) in oxidative stress mediated by hepatitis B virus X protein expression

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The matrix, X, of normalized gene abundances with samples on the rows and the biomarker genes on the columns was provided to the opls function of the ropls package with parameters predI = 2 (derive 2 PCA components) and permI = 100 (perform 100 random permutations of the class labels to evaluate predictive performance) to predict the biological condition (Y)