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And, surprisingly, the deficiency in LAC is even stronger in patients that dont respond to standard antidepressants. These results suggest that LAC levels may be used as an effective biomarkermeaning, a measurable physiological trait that can indicate the presence of disease (sometimes in combination with other diagnostic techniques)

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Excessive generation of reactive oxygen species (ROS) has been identified as a major pathological driver, sustaining pro-inflammatory cascades and compromising fibroblast functionality, thereby underscoring the critical role of redox balance and antioxidant-based interventions in promoting regenerative healing

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Reulen HJ, Graham R, Spatz M et al (1977) Role of pressure gradients and bulk flow in dynamics of vasogenic brain edema

Functional Metabolism Markers Could oxalates or amino acids be contributing to my symptoms