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Introduction Vitamin B 12 (cobalamin) deficiency is a major health concern worldwide (Stabler and Allen, 2004

Compared with EtOH-fed WT mice, KO mice were less susceptible to EtOH-induced deleterious effects, including body weight loss (reflected by less body weight gain), liver weight gain and hepatocyte damage (reflected by plasma ALT activity) (Table 1)

These molecules facilitate leukocyte adherence to the endothelium, which promotes inflammation and contributes to atherosclerosis

References 1 AisenPEnnsCWessling-ResnickM

Silymarin is also protective against several classes of nephrotoxic drugs, in particular cisplatin and doxorubicin