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Indicators of oxidative stress in semen analysis include: Poor sperm motility (asthenozoospermia) Poor sperm morphology (teratozoospermia) Elevated numbers of round cells, including leukocytes (white blood cells), which can be a sign of infection Increased levels of sperm DNA damage in DNA fragmentation analysis There are actually tests that can more specifically measure levels of oxidative stress in semen, such as directly measuring ROS levels, total antioxidant capacity (TAC), and the oxidative stress marker MDA ( malondialdehyde )

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In addition, persons with liver disease often have evidence of platelet-associated antibodies, 218 although their contribution to low platelet counts in liver disease is questionable

Qin et al., 2025