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Do not freeze reconstituted solution, do not shake (swirl gently), and discard if the solution becomes cloudy or shows particulates

Reduced CYP3A4 activity could slow isotretinoin metabolism, raising plasma exposure and amplifying both efficacy and toxicity

Berberine may cause digestive side effects in some people

Gene set enrichment analysis (GSEA) was performed using the fgsea package, FA metabolism-related pathway enrichment was analyzed via the GSVA package, and Gene Ontology (GO) analysis was conducted with the clusterProfiler package

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176 Glycine Glycine is a conditionally essential amino acid found in plant and animal proteins